甘蔗及甘蔗汁中的霉菌毒素污染:首次报道多种霉菌毒素检测及人体黄曲霉毒素B1和M1的暴露评估

Mycotoxin Contamination in Sugarcane Grass and Juice: First Report on Detection of Multiple Mycotoxins and Exposure Assessment for Aflatoxins B-1 and G(1) in Humans

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中文摘要:本文研究了上埃及人类消费的甘蔗及甘蔗汁中多种有毒真菌和细菌代谢物的自然发生情况。目标分析物的量化采用dilute and shoot结合液相色谱-串联质谱(LC-MS/MS)法。分别在21种甘蔗和40种甘蔗汁中发现了29种真菌和33种细菌代谢物,且有甘蔗中的浓度高于甘蔗汁的趋势。通过问卷调查了艾斯尤特市居民消费甘蔗汁的的情况并评估了膳食暴露,结果显示AFB1暴露随性别及季节(夏季和冬季)而不同。估算的季节性暴露范围为冬季每天0.20-0.40ng/kg体重,夏季每天0.38-0.90ng/kg体重。
外文摘要:This study was conducted to investigate the natural co-occurrence of multiple toxic fungal and bacterial metabolites in sugarcane grass and juice intended for human consumption in Upper Egypt. Quantification of the target analytes has been done using the "dilute and shoot" approach followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS). A total number of 29 and 33 different metabolites were detected in 21 sugarcane grass and 40 juice samples, respectively, with a trend of concentrations being higher in grass than in juice. Among the regulated mycotoxins, only aflatoxin B₁ (AFB₁) and aflatoxin G₁ (AFG₁) were detected. The prevalence of AFB₁ was in 48% of grass samples and in 58% of juice with a maximum concentration of 30.6 μg/kg and 2.10 μg/kg, respectively. AFG₁ was detected in 10% of grass samples (7.76 μg/kg) and 18% of juice samples (34 μg/kg). Dietary exposure was assessed using a juice frequency questionnaire of adult inhabitants in Assiut City. The assessment revealed different levels of exposure to AFB₁ between males and females in winter and summer seasons. The estimated seasonal exposure ranged from 0.20 to 0.40 ng/kg b.w./day in winter and from 0.38 to 0.90 ng/kg b.w./day in summer.
外文关键词:mycotoxins;sugarcane;sugarcane juice;aflatoxins;LC-MS/MS;exposure assessment
作者:Abdallah, MF;Krska, R;Sulyok, M
作者单位:Assiut Univ
期刊名称:TOXINS
期刊影响因子:3.571
出版年份:2016
出版刊次:11
点击下载:甘蔗及甘蔗汁中的霉菌毒素污染:首次报道多种霉菌毒素检测及人体黄曲霉毒素B1和M1的暴露评估
  1. 编译服务:农产品质量安全
  2. 编译者:虞德容
  3. 编译时间:2017-03-22