中文摘要：据报道常见的饲料污染物脱氧雪腐镰刀菌烯醇（DON）对猪胃无腺区（PN）的形态有影响。而且，已知细磨饲料引起PN溃疡及其他症状加重而粗磨饲料则对此有保护作用。迄今为止饲料研磨细度与DON污染间的相互作用尚无研究。为此，本研究测试了有／无DON污染的小麦的细磨和粗磨饲料对仔猪生长性能与健康状况，包括胃完整性的影响。研究发现DON污染加剧了细磨饲料对胃粘膜完整性的不利影响。
外文摘要：The common feed contaminant deoxynivalenol (DON) was reported to influence the morphology of the pars nonglandularis (PN) of porcine stomach. Moreover, finely ground feed is known to trigger the development of ulcers and other pathologies of PN while coarsely ground feed protects from such lesions. The interactions between grinding fineness and DON contamination of feed were not examined so far. Therefore, both finely and coarsely ground feeds were tested either in the absence or presence of a DON contaminated wheat on growth performance and health of rearing piglets, including stomach integrity. DON contamination significantly reduced feed intake and serum albumin concentration with this effect being more pronounced after feeding the coarsely ground feed. Albeit at a higher level, albumin concentration was also reduced after feeding the finely ground and uncontaminated feed. Finely ground and DON-contaminated feed caused a significantly more pronounced lymphoplasmacytic infiltration both of PN and pars glandularis, partly paralleled by lymph follicle formation and detritus filled foveolae and tubes suggesting a local immune response probably triggered by epithelial lesions. It is concluded that DON contamination of feed exacerbates the adverse effects of finely ground feed on stomach mucosal integrity.
外文关键词：deoxynivalenol；pig；feed grinding fineness；stomach pathology
作者：Daenicke, S；Beineke, A；Berk, A；Kersten, S
作者单位：Fed Res Inst Anim Hlth
期刊名称：TOXINS
期刊影响因子：3.571
出版年份：2017
出版刊次：1
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