中文摘要:本文通过研究我国采集的一种海洋镰刀菌的化学成份,表征了一种新的白僵菌素类似物,白僵菌素K。并通过详细的光谱分析,包括一维和二维NMR法和HRMS研究了它的结构。白僵菌素K具有显著的抗白色念珠菌活性,IC50值为6.25mug/mL。
外文摘要:Chemical investigation of a Chinese collection of a marine-derivedfungus, Fusarium sp., led to the characterization of beauvericin K, a new analogue of beauvericin. The structure of the new compound was elucidated by detailed spectroscopic analysis, including 1D and 2D NMR methods, and HRMS. Beauvericin K showed significant activity against the yeast Candida albicans with an IC50 value of 6.25 mu g/mL.
外文关键词:Beauvericin K;Antifungal;Marine-derived fungus;Fusarium sp.
作者:Xu, XL;Zhao, SJ;Yu, Y;Chen, ZK;Shen, HH;Zhou, L
作者单位:China Univ Geosci
期刊名称:NATURAL PRODUCT COMMUNICATIONS
期刊影响因子:0.884
出版年份:2016
出版刊次:12
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