中文摘要：根据WTO推荐程序，本文对阿根廷四个年龄组人口进行了慢性膳食风险评估。从阿根廷国家健康营养调查的常规食品消费数据中的最大残留量，本文第一次获得了308种农药的国家理论每日最大摄入量。通过对比国家理论每日最大摄入量和每日可接受摄入量来进行风险评估，此外，每一种化合物的国家理论每日最大摄入量均大于每日可接受摄入量的65%，并通过概率分析对每日可接受摄入量超标的可能性进行量化。结果发现，6-30个月的儿童、2-5岁的儿童、孕妇和10-49岁的女性分别有27、22、10和6种活性成分超过了每日可接受摄入量的100%，超过每日可接受摄入量的农药中有一些农药（呋喃丹、二嗪磷、敌敌畏、乐果、甲基砜吸磷和甲基溴）均出现在四个年龄组内，牛奶、苹果、土豆和西红柿是这些杀虫剂摄入最多的食物。该研究在改进风险评估、相关法规和监督活动方面起到一定的作用。
外文摘要：A chronic dietary risk assessment for pesticide residues was conducted for four age groups of the Argentinian population following the procedure recommended by the WHO. The National Theoretical Maximum Daily Intake (NTMDI) for 308 pesticides was calculated for the first time, using the Maximum Residue Limits (MRLs) from several Argentinean regulations and food consumption data from a comprehensive National Nutrition and Health Survey. The risk was estimated by comparing the TMDI with the Acceptable Daily Intakes (ADI) identified by various sources. Furthermore, for each of the compounds with a TMDI >65% of the ADI, a probabilistic analysis was conducted to quantify the probability of exceeding the ADI. In this study 27, 22, 10, and 6 active ingredients (a.i.) were estimated to exceed the 100% of the ADI for the different population groups: 6-23month-old children, 2-5year-old children, pregnant women, and 10-49year-old women, respectively. Some of these ADI-exceeding compounds (carbofuran, diazinon, dichlorvos, dimethoate, oxydemeton-methyl and methyl bromide) were found in all four of these groups. Milk, apples, potatoes, and tomatoes were the foods that contributed most to the intake of these pesticides. The study is of primary importance for the improvement of risk assessment, regulations, and monitoring activities.
外文关键词：Pesticides, MRL, TMDI, dietary risk assessment, food consumption
作者：Maggioni, Dario A.; Signorini, Marcelo L.; Michlig, Nicolas; Repetti, Maria R.; Sigrist, Mirna E.; Beldomenico, Horacio R.
作者单位：Natl Univ Littoral, Program Res & Anal Chem Residues & Contaminants P, Fac Chem Engn, Santiago Estero 2654, RA-3000 Santa Fe, Argentina.
期刊名称：OURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES
期刊影响因子：1.247
出版年份：2017
出版刊次：7
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