中文摘要：本文提出采用超高效液相色谱-串联质谱法对小麦粉进行农药或杀菌剂残留多重分析，为了获得更好的富集因子和较小的基质效应，本文开发了一个基于填充吸附剂微萃取的高效且快速的清洗方法。本研究目标分析物为广泛应用于小麦的25种具有不同理化性质和作用机理的农药，比如有机磷、氨基甲酸酯、新烟碱类杀虫剂等乙酰胆碱酯酶抑制剂和咪唑类、三唑类等抑制麦角甾醇。根据SANCO/12571/2013指南，该方法适用于对小麦粉中25种农药残留检测。
外文摘要：An ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS) method for multiclass analysis of pesticide and fungicide residues in wheat flour based is presented. An efficient and rapid cleanup based on microextraction by packed sorbent (MEPS) has been developed in order to have a good enrichment factor together with a low matrix effect. The target analytes were 25 pesticides widely used in wheat, with different physico-chemical characteristics and different mechanism of action: acetylcholinesterase inhibitors such as organophosphorus, carbamates, neonicotinoids, and inhibitors of ergosterol such as imidazoles and triazoles. MEPS was shown to be successful with reduction of the amount of solvent required and possibility of automation of the cleanup procedure. The whole method was then validated according to the SANCO/12571/2013 guidelines, proving its suitability as confirmation method for the selected analytes.
外文关键词：Pesticides, Wheat flour, MEPS, UHPLC-MS/MS, Multiclass analysis
作者：Di Ottavio, Francesca; Della Pelle, Flavio; Montesano, Camilla; Scarpone, Rossana; Escarpa, Alberto; Compagnone, Dario; Sergi, Manuel
作者单位：Univ Teramo, Fac Biosci & Technol Food Agr & Environm, Teramo, Italy.
期刊名称：Food Analytical Methods
期刊影响因子：2.167
出版年份：2017
出版刊次：6
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