中文摘要:快速准确地检测病原细菌是食品安全和公共卫生领域的研究热点。表面增强拉曼散射由于具有灵敏度高、速度快、成本低、可复用性强、可移植性强等优点,一直被认为是一种强大而有吸引力的病原菌检测技术。因此,本文的研究主旨是对基于标签和无标记策略的表面增强拉曼散射技术快速检测病原细菌的研究进展进行综述。本文首先简短地介绍了表面增强拉曼散射技术的应用教程,然后综述了基于标签和无标记策略的表面增强拉曼散射技术快速检测病原细菌的最新研究进展,包括表面增强拉曼散射光谱相对完整的介绍。此外,还讨论了多功能表面增强拉曼散射检测平台,并对表面增强拉曼散射技术可以作为实时病原细菌检测的可靠工具进行了展望。
外文摘要:Rapid, accurate detection of pathogen bacteria is a highly topical research area for the sake of food safety and public health. Surface-enhanced Raman scattering (SERS) is being considered as a powerful and attractive technique for pathogen bacteria detection, due to its sensitivity, high speed, comparatively low cost, multiplexing ability and portability. This contribution aims to give a comprehensive overview of SERS as a technique for rapid detection of pathogen bacteria based on label and label-free strategies. A brief tutorial on SERS is given first of all. Then we summarize the recent trends and developments of label and label-free based SERS applied to detection of pathogen bacteria, including the relatively complete interpretation of SERS spectra. In addition, multifunctional SERS platforms for pathogen bacteria in matrix are discussed as well. Furthermore, an outlook of the work done and a perspective on the future directions of SERS as areliable tool for real-time pathogen bacteria detection are given.
外文关键词:Pathogen bacteria, Surface-enhanced Raman scattering, Label method, Label-free method, Multifunctional detection platform
作者:Liu, Yu; Zhou, Haibo; Hu, Ziwei; Yu, Guangxia; Yang, Danting; Zhao,Jinshun
作者单位:Ningbo Univ, Dept Preventat Med, Zhejiang Prov Key Lab Pathol & Physiol Technol, Sch Med, Ningbo 315211, Zhejiang, Peoples R China.
期刊名称:BIOSENSORS & BIOELECTRONICS
期刊影响因子:7.78
出版年份:2017
出版刊次:8
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