中文摘要：立枯丝核菌和尖孢镰刀菌是非常著名的植物病原菌，在全球广泛传播，引发最具破坏性的疾病之一，给作物生产带来严重减产。为了找到有效的杀菌剂控制植物病原体，本研究评估了肉桂醛、丁香酚衍生物抗立枯丝核菌和尖孢镰刀菌的结构-活性关系。本方法可能对今后寻找杀菌化合物有帮助。
外文摘要：Rhizoctonia solani and Fusarium oxysporum are very well known phytopathogens with worldwide spread that cause one of the most destructive diseases, resulting significant yield losses in crop production. In order to find effective fungicides for controlling phytopathogen, the structure-activity relationships of cinnamaldehyde and eugenol derivatives against R. solani and F. oxysporum were evaluated. Additionally, the composition and fungicidal activity of Cinnamomum cassia and Syzygium aromatica essential oils was assessed. Cinnamaldehyde (49.75%) is the major compound in cinnamon bark oil, and eugenol (89.17%) is most abundant in clove bud oil. The clove bud oil exhibited good antifungal activities against R. solani and F. oxysporum (IC50 = 106.5 and 149.9 μg/mL, respectively). Cinnamon bark oil showed a lower activity than clove bud oil. The fungicidal activity of cinnamaldehyde (IC50 = 75.4 and 156.9 μg/mL, respectively) and eugenol (IC50 = 58.9 and 52.9 μg/mL, respectively) against R. solani and F. oxysporum was also evalutated. Comparisons of the antifungal activities of cinnamaldehyde and eugenol derivatives revealed that α-methylcinnamaldehyde, α-methylcinnamic acid, methyleugenol, acetyleugenol, isoeugenol, methylisoeugenol, and acetylisoeugenol showed good antifungal activities against R. solani and F. oxysporum. In structure-activity relationships, the fungicidal activity of cinnamaldehyde derivatives could be related to conjugated double bond and the length of CH chain outside the ring. In addition, the presence of the lipophilicity may have a considerable influence on the toxicity of phenylpropenes. The present approach may help future work in the search for fungicidal compounds.
外文关键词：Antifungal activity；Cinnamaldehyde derivatives；Eugenol derivatives；Rhizoctonia solani；Fusarium oxysporum
作者：Xie, YJ；Huang, QQ；Wang, ZJ；Cao, HY；Zhang, DY
作者单位：Zhejiang A&F Univ
期刊名称：INDUSTRIAL CROPS AND PRODUCTS
期刊影响因子：3.449
出版年份：2017
出版刊次：3
点击下载：肉桂醛、丁香酚衍生物抗植物病原真菌的结构-活性关系