中文摘要：肉鸡是生长速度快的单胃动物，它被认为是转基因和非转基因谷物安全性和营养性评价的敏感实验物种。转基因大豆das44406-6表达三种抗除草剂蛋白。本文进行了为期42天的肉鸡饲喂实验来评价转基因大豆的营养健康与安全，饲喂饮食中分别包含了转基因大豆das44406-6、非转基因大豆、近等基因大豆和常规大豆。经过6周不用饮食的饲喂试验后，测量肉鸡的性能和体重参数。研究发现，在13项测量指标中，只有饲喂转基因大豆das44406-6和近等基因大豆的肉鸡大腿重量不同。而饲喂转基因大豆das44406-6和其他非转基因品种的肉鸡大腿重量没有显著差别。研究结果表明，转基因大豆das44406-6的营养价值相当于常规品种。
外文摘要：Broiler chickens are fast growing monogastric animals considered a sensitive test species to evaluate the safety and nutritional equivalence between transgenic and non-transgenic grains as part of the human safety evaluation process. DAS-44406-6 soybean expresses three herbicide-tolerant proteins: the aryloxyalkanoate dioxygenase-12 (AAD-12) enzyme which provides tolerance to 2,4-dichlorophenoxyacetic acid (2,4-D) herbicides, the double-mutant 5-enolpyruvylshikimate-3-phosphate synthase (2mEPSPS) enzyme encoded by a modified version of the epsps gene from maize (Zea mays), which provides tolerance to glyphosate herbicides, and the phosphinothricin acetyltransferase (PAT) enzyme from Streptomyces viridochromogenes, which provides tolerance to glufosinate herbicides. A 42-day broiler study was conducted with diets containing toasted DAS-44406-6 soybean meal to evaluate nutritional wholesomeness and safety compared with non-transgenic, near-isoline soybean and conventional comparators. The study used a randomized complete block design with five dietary treatments assigned randomly within six blocks of 12 pens per treatment, with 10 birds per pen. Broiler performance and carcass parameters were measured over a 6-week period of exposure to diets containing different sources of toasted soybean meal and hulls. Among the 13 endpoints measured, only thigh weight was numerically different between birds fed DAS-44406-6 soybean meal and those fed isoline soybean meal. However, no significant differences to thigh weight were observed between birds fed DAS-44406-6 soybean and any of the non-transgenic reference varieties. Results indicate that DAS-44406-6 soybeans are nutritionally equivalent to conventional varieties.
外文关键词：DAS-44406-6; nutrition; broiler chickens; soybean
作者：Papineni, Sabitha; Fletcher, Dale W.; Cromwell, Gary L.; 等
作者单位：Dow AgroSci LLC
期刊名称：POULTRY SCIENCE
期刊影响因子：1.908
出版年份：2017
出版刊次：5
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