中文摘要：本研究涉及2个批次（批次I和II）的新型sahaj vati草药配方的化工标准化和黄曲霉毒素抑制及抗氧化活性。该配方通过将shilajeet（夏季山区的浓稠渗出物）、guggul（穆库没药）、haridra(姜黄)以及chitrak (白花丹)与水磨Agnimantha kwatha（豆腐豆）进行混合制备。研究表明该新型配方能够抗脂质过氧化及黄曲霉毒素污染，提高保健品的保质期，具有保健品附加值，值得推荐。
外文摘要：The present investigation deals with chemical standardization and aflatoxin inhibitory and antioxidant activity of a herbomineral formulation, sahaj vati prepared in two batches (batch I and II) by mixing shilajeet (thick exudates of the mountain during summer season), guggul (Commiphora mukul (stocks) hook.), haridra (Curcuma longa L) and chitrak (Plumbago zeylanica L) with levigation of Agnimantha kwatha (Premna mucronata L). Batch I was prepared by mixing shilajeet, guggul, haridra and chitrak in equal proportion (25% each by weight) while batch II comprised shilajeet (44.7%), guggul (44.7%), haridra (4.8%) and chitrak (5.8%) by weight. Sahaj vati II showed highest (96%) inhibition of aflatoxin production at concentration of 10 000 mu g/ml. Suddha guggul exhibited strong antioxidant activity showing lowest IC50 at concentration of 20.56 mu g/ml. Based on these findings, the newly formulated herbomineral formulation could be recommended for value addition of nutraceuticals by enhancing their shelf life against lipid per oxidation and aflatoxin contamination.
外文关键词：Herbomineral formulation；shahaj vati；antiaflatoxigenic；antioxidant,nutraceuticals
作者：Yadav,KD；Dwivedy,AK；Chaudhary,AK；Dubey,NK
作者单位：Banaras Hindu Univ
期刊名称：INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES
期刊影响因子：0.762
出版年份：2017
出版刊次：1
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