中文摘要：之前，一些研究显示使用粘土粘合剂吸附陆生动物饲料中的黄曲霉毒素获得成功；然而，还没有吸附剂被批准用于治疗或预防黄曲霉毒素中毒。本研究每天用2、4ppm AFB1搭配0.5或1.0%钙膨润土(4TX) 饲喂尼罗罗非鱼，10周后评估其生长性能、条件指数、近似组分及蛋白质沉积率，并分析了鱼肌肉组织中的AFB1残留。为了比较日粮中不同类型的4TX粘土的功效，分别用干粉混合（PM）或水分散（WD）的形式添加。结果表明，与WD相比，4TX粘土以PM形式添加时减轻AFB1诱导的罗非鱼毒性的功效更大。
外文摘要：Previous research has shown some success using clay-based binders to adsorb aflatoxin in terrestrial animal feeds; however, no adsorbent has been approved for the prevention or treatment of aflatoxicosis. In the present study, growth performance, condition indices, proximate composition and protein retention efficiency of Nile tilapia were evaluated along with analysis of aflatoxin-B-1 residuals in muscle tissues of fish fed diets containing AFB(1) at 2 and 4 ppm along with either 0.5 or 1.0% calcium bentonite clay (4TX) for a period of 10 weeks. To compare the efficacy of inclusion type of 4TX clay in the diet, it was added as either a dry powder mix (PM) or water dispersed (WD) form. Inclusion of AFB1 at concentrations of 2 and 4 ppm significantly (P < 0.05) reduced weight gain, feed efficiency ratio (FER), hepatosomatic index (HSI), muscle ratio, whole-body crude lipid and protein retention efficiency (PRE), regardless of the inclusion of 4TX in the diets. However, addition of 4TX as PM in the diet improved some of those fish responses. In particular, at the 2 ppm AFB1 level, 1.0% 4TX PM tended to improve % weight gain (831%) as compared to 1.0% 4TX WD (707%) or 0.5% 4TX WD (708%). Also there was a significant difference in HSI when contrasted between basal vs clay PM (P < 0.001) and dispersion type, WD vs PM (P= 0.022). Whole-body % moisture (P= 0.036) and crude lipid (P= 0.014) also were significantly affected by AFB1 in diets at both 2 and 4 mg/kg. Contrast between basal vs clay WD also showed a significant difference (P= 0.046) in whole-body crude lipid content. The AFB(1) residues in muscle tissues were only detected in fish exposed to the highest inclusion level of AFB(1) (4 ppm). Addition of 4TX in the diets significantly reduced bioaccumulation of AFB1 in muscle of Nile tilapia, especially when included in PM (0.43 +/- 0.03 ng/g) compared to WD (1.87 +/- 1.32 ng/g) form. Thus, greater efficacy of 4TX clay was observed when included as PM compared to WD in alleviating AFB(1) induced toxicity in tilapia.
外文关键词：Nile tilapia；Calcium bentonite clay；Aflatoxin；Muscle residues；Powder mix；Water dispersed
作者：Hussain, D；Mateen, A；Gatlin, DM
作者单位：G C Univ
期刊名称：AQUACULTURE
期刊影响因子：1.893
出版年份：2017
出版刊次：10
点击下载：通过钙膨润土降低黄曲霉毒素B1（AFB1）的毒性：对尼罗罗非鱼（Oreochromis niloticus）的生长性能、条件指数和体内残留AFB1生物累积的影响