中文摘要：使用UHPLC-MS/MS开发了一种可靠、快速而简单的方法用于测定水果馅饼干、饼干、干果和水果果酱粗提物中的黄曲霉毒素B1（AFB1）、G1（AFG1）、B2（AFB2）、G2（AFG2）、赭曲霉毒素A（OTA）、脱氧雪腐镰刀菌烯醇（DON）、玉米赤霉烯酮（ZEA）、HT2毒素和T2毒素。该方法已成功地应用于39个水果馅饼干、34个饼干、14个干果和10个果酱样品。结果表明，大多数样品符合相关规定。本研究首次评估了上述真菌毒素对儿童、青少年和成年人的组合膳食暴露情况。估计的组合膳食暴露量都低于假设的预测可能出现风险的建议值。
外文摘要：A reliable, fast and simple method using UHPLC-MS/MS was developed for the determination of aflatoxins B-1 (AFB1), G(1) (AFG1), B-2 (AFB2) and G(2) (AFG2), ochratoxin A (OTA), deoxynivalenol (DON), zearalenone (ZEA), HT-2 toxin and T-2 toxin in crude extracts of biscuits with fruit filling, cookies, dried fruits and fruit jams. The method was successfully demonstrated on 39 samples of biscuits with fruit filling, 34 cookies, 14 dried fruits and 10 fruit jams. The mycotoxins detected in biscuits samples were ZEA, OTA, T-2 and AFB1 with an average concentrations of positive samples of 2.64, 4.10, 8.13 and 1.32 mu gkg(-1), respectively; while the mycotoxins detected in jam samples were AFB1, OTA, T-2 and AFB2 with an average concentrations of positive samples of 2.00, 17.7, 4.37 and 1.15 mu gkg(-1), respectively. The results showed that the majority of samples were in compliance with relevant regulations. However in eight samples of biscuits and three samples of fig jam the contents of OTA were higher than the existing OTA limits. The combined dietary exposure of selected mycotoxins was estimated for the first time for children, adolescents and adults. The estimated combined dietary exposures were all lower than the proposed value assumed to predict a possible risk scenario.
外文关键词：Mycotoxins； crude extract analysis； biscuits； dried fruits； risk assessment
作者：Skrbic, B； Antic, I； Cvejanov, J
作者单位：Univ Novi Sad
期刊名称：FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT
期刊影响因子：1.878
出版年份：2017
出版刊次：6
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