中文摘要:本研究用包含了蒸馏水和乙醇或20-400μg/mlAFB1暴露超72小时的接触纸试验系统,评估了黄曲霉毒素B1(AFB1)对赤子爱胜蚓(Savigny 1826)的毒性。结果证实了赤子爱胜蚓及基于该种生物的标准化方法(OECD 207 1984) 可用于霉菌毒素相关的毒性研究。
外文摘要:In this study, aflatoxin B1 (AFB1) toxicity toward the earthworm Eisenia fetida (Savigny 1826) was evaluated in contact paper test systems containing distilled water and ethanol or 20 to 400 μg/ml of AFB1 over 72 h of exposure. The results indicated that AFB1 could induce significant damage to earthworms (coiling, curling, excessive mucus secretion, clitellum swelling) at greater than 75 μg/ml. Moreover, AFB1 had harmful effects on E. fetida (degenerative changes such as bulging of the clitella regions) at levels higher than 150 μg/ml. The calculated LD50 was 168.5 μg/ml. These findings confirm that E. fetida and standardized methods based on this organism (OECD 207 1984) are applicable and useful in mycotoxin related toxicity studies.
外文关键词:Aflatoxin B-1;Contact paper test;Earthworm;Eisenia fetida
作者:Szabo-Fodor, J;Bors, I;Nagy, G;Kovacs, M
作者单位:Kaposvar Univ
期刊名称:MYCOTOXIN RESEARCH
期刊影响因子:2.0
出版年份:2017
出版刊次:2
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