中文摘要：本研究评估了从伊朗市场采集的88个样品，包括干桑椹、红枣、无花果和杏中黄曲霉毒素（AFs）和赭曲霉毒素A(OTA)污染的水平。估算了暴露限值（MOE），评估了膳食摄入黄曲霉毒素B1(AFB 1)和OTA的风险。据估算的MOE来看，伊朗通过消费干果产生的AFs暴露对消费者健康构成了潜在的风险；而OTA水平在所有类型的干果中均低于EU规定的推荐水平(10μg/kg)且MOE>10000，消费者无需顾虑。
外文摘要：In this study, the contamination levels of aflatoxins (AFs) and ochratoxin A (OTA) in 88 collected samples from Iran's market including dried mulberry, date, fig, and apricot were evaluated. The margin of exposure (MOE) was estimated to assess the risk of dietary intake of aflatoxin B1 (AFB1) and OTA. The incidence of AFB1 in dried mulberry, date, fig and apricot samples was 45.5, 40.9, 59.1, and 81.8%, respectively. Although the mean total AFs content in contaminated samples of date (2.61 μg/kg), fig (3.43 μg/kg) and apricot (2.91 μg/kg) was lower than the maximum limit set in the European Union (EU) (4 μg/kg), dried mulberry samples showed a higher contamination level (4.12 μg/kg). The co-occurrence of OTA and AFs were noted in 4 (18.9%), 2 (9.1%), 4 (18.2%), and 10 (45.5%) in the dried mulberry, date, fig and apricot samples, respectively. Based on the calculated MOE, the dietary exposure to AFs through the consumption of dried fruit in Iran poses a potential risk to consumer health. OTA was detected in 45.45%, 22.72%, 45.45%, and 50% of mulberry, date, fig and apricot samples, respectively. However, OTA levels in all types of dried fruit were below recommended level in EU regulation (10 μg/kg) and MOE >10000, representing no toxicological concerns for consumers.
外文关键词：Aflatoxins；Ochratoxin A；Risk assessment；Dried fruit；HPLC；Dietary exposure
作者：Heshmati, A；Zohrevand, T；Khaneghah, AM；Nejad, ASM；Sant'Ana, AS
作者单位：Hamadan Univ Med Sci
期刊名称：FOOD AND CHEMICAL TOXICOLOGY
期刊影响因子：3.584
出版年份：2017
出版刊次：8
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