中文摘要：不同种类曲霉和青霉产生的黄曲霉毒素和赭曲霉素是重要的霉菌毒素。本研究旨在探索发霉饲料对白来亨(WLH)鸡的毒性病理学效应，并评估酿酒酵母泥(DYS)抗霉菌毒素的改善作用。研究表明在发霉饲料中添加2%DYS后，与对照组相比，几乎所有研究参数都正常；而添加1%DYS则部分改善了霉菌毒素的毒性作用。
外文摘要：Aflatoxin and ochratoxin are important mycotoxins formed by different species of Aspergillus and Penicillium. The purpose of this study was to check the toxic pathological effects of moldy feed in White Leghorn (WLH) hens and to estimate the amelioration by distillery yeast sludge (DYS) against mycotoxins. For this purpose, 100, 40-weeks old WLH hens were procured and kept under standard management conditions. Birds were divided in five equal groups. Birds were kept on moldy feed (ochratoxin A (OTA): 56g/kg and aflatoxin B1 (AFB1): 136g/kg) mixed with 0, 0.5, 1 and 2% DYS/kg moldy feed. Group A served as control. The birds of the control group were active, with normal feed intake and feathers as compared to moldy feed and in combination with DYS. The attraction toward feed and water, feed intake, body weight gain, egg production (%) and egg weight significantly (p0.05) decreased in the moldy group as compared to control group. The relative weight of liver, kidney, heart and spleen increased significantly in groups B (moldy feed) and C (moldy feed+0.5% DYS) as compared to control group. Total erythrocyte count (TEC), total leukocyte count (TLC), hemoglobin (Hb) and hematocrit lowered significantly in B and C groups. Moldy feed in liver, kidney and spleen produced pathological changes like enlargement, ecchymotic hemorrhages on the surface, vacuolar degeneration, cellular infiltration, congestion, etc. Almost all parameters studied were normal compared to control group with the addition of 2% DYS in moldy feed while 1% DYS partially ameliorated the toxic effects of mycotoxins.
外文关键词：Aflatoxin; ochratoxin；moldy feed；White Leghorn layers；distillery yeast sludge
作者：Khan, A；Aalim, MM；Khan, MZ；Saleemi, MK；He, C；Naseem, MN；Khatoon, A；AF Khan, Ahrar；Aalim, Muhammad Mustjab；Khan, M. Zargham；Saleemi, M. Kashif
作者单位：China Agr Univ
期刊名称：TOXIN REVIEWS
期刊影响因子：0.857
出版年份：2017
出版刊次：3
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