中文摘要：本研究成功研发了一种基于石墨烯的高性能微电机策略，可同步、快速、可靠地检测两种备受关注的霉菌毒素（伏马菌素B1，FB1和赭曲霉毒素A，OTA）。研究表明，该方法所获得的结果良好，使催化电机应用于未开发的新领域，如食品安全诊断的发展前景令人振奋。
外文摘要：A high-performance graphene-based micromotor strategy for simultaneous, fast and reliable assessment of two highly concern mycotoxins (fumonisin B1, (FB1) and ocratoxin A, (OTA)) has successfully been developed. The assay principle is based on the selective recognition from aptamers to the target mycotoxins and further “on-the-move” fluorescence quenching of the free aptamer in the outer layer of unmodified reduced graphene (rGO; sensing layer), micromotors. Template-prepared rGO/platinum nanoparticles (PtNPs) tubular micromotors, were synthesized rapidly and inexpensively by the direct electrodeposition within the conical pores of a polycarbonate template membrane. The new wash-free approach offers using just 1 µL of sample, a simultaneous and rapid “on-the-fly” detection (2 min) with high sensitivity (LODs of 7 and 0.4 ng/mL for OTA and FB1, respectively), and high selectivity. Remarkable accuracy (Er<5%) during the mycotoxin determination in certified reference material (CRM) as well as excellent quantitative recoveries (96-98%) during the analysis of food samples were also obtained. The excellent results obtained allow envisioning an exciting future for the development of novel applications of catalytic micromotors in unexplored fields such as food safety diagnosis.
作者：Molinero-Fernandez, A；Moreno-Guzman, M；Lopez, MA；Escarpa, A
作者单位：Univ Alcala De Henares
期刊名称：ANALYTICAL CHEMISTRY
期刊影响因子：5.886
出版年份：2017
出版刊次：20
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