中文摘要：本文在分辨率为140000（m/z 200）和30000（m/z 556）的情况下，分别采用液相色谱- Orbitrap质谱仪和液相色谱-飞行时间质谱仪在全扫描模式下检测茶叶农药残留。即在0.1和0.01 mg/kg加标水平下对茶叶中146种农药残留进行检测，并从回收率、日内和日间精密度、选择性、线性度和基质效应等方面进行了比较。结果显示：检测结果具有可比性，且大多数农药残留的回收率、日内和日间精密度均在可接受范围内，但由于液相色谱- Orbitrap质谱仪分辨率更高，其灵敏度和选择性优于液相色谱-飞行时间质谱仪。但尽管液相色谱- Orbitrap质谱仪具有高分辨率和+/- 3 ppm的窄窗，仍可观察到共基质成分干扰且全扫描数据不足以识别，因此碎片离子等附加信息成为必需。
 
外文摘要：Liquid chromatography (LC)-Orbitrap mass spectrometry (MS) and  LC-time-of-flight (TOF) MS operating in full scan mode at a mass resolution of 140,000 (m/z 200) and 30,000 (m/z 556), respectively, were compared for quantification of pesticide residues in tea. Both methods were validated for 146 pesticides at spike levels of 0.1 and 0.01 mg/kg and compared in terms of recovery, intra- and inter-day precisions, selectivity, linearity, and matrix effect. The results of both analyses  were comparable, and recovery and intra- and inter-day precisions were within the acceptable ranges for most pesticides. LC-Orbitrap MS was slightly superior to LC-TOF MS in terms of sensitivity and selectivity due to its higher resolution. However, even using high-resolution LC-Orbitrap MS with a narrow mass window of +/- 3 ppm, interference by coeluting matrix components was observed, indicating that full scan data are insufficient for unequivocal identification, and additional information such as fragment ions is necessary.
 
外文关键词：Pesticide; multiresidue analysis; tea; liquid chromatography-Orbitrap mass spectrometry; liquid chromatography-time-of-flight mass spectrometry
作者：Shizuka Saito-Shida;Tomoko Hamasaka;Satoru Nemoto;Hiroshi Akiyama
作者单位：Division of Foods, National Institute of Health Sciences, Tonomachi 3-25-26, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan
期刊名称：FOOD CHEMISTRY
期刊影响因子：4.529
出版年份：2018
出版刊次：2
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