中文摘要：因黄曲霉毒素B1（AFB1）普遍存在，以及其致畸、致癌和致突变作用，能引发严重的公共健康威胁。本研究旨在评估AFB1的毒性并评价枯草芽孢杆菌ANSB060对黄河鲤鱼黄曲霉毒素中毒的改善效能。结果表明ANSB060对黄河鲤鱼黄曲霉毒素中毒具有保护作用，在饲料工业中具有广阔的应用前景。
外文摘要： Aflatoxin B1 (AFB1) elicits serious threats to public health due to its widespread occurrence, as well as its teratogenic, carcinogenic and mutagenic effects. This study aimed to evaluate the toxicity of AFB1 and assess the ameliorative efficacy of Bacillus subtilis ANSB060 on aflatoxicosis in Yellow River carp. A total of 750 juvenile Yellow River carp were allocated into five dietary treatments for 60 days. Diet C0 represented for the negative control, diet M0 containing about 50 μg AFB1/kg diet represented for the positive control, and diet M0.25, M0.5 and M1.0 was diet M0 supplemented with B. subtilis ANSB060 at a dose of 0.25 × 109, 0.5 × 109 and 1.0 × 109 CFU/kg diet, respectively. The results showed that supplementation of strain ANSB060 restored the reduced body weight and enhanced feed conversion ratio of carp induced by AFB1 towards normal. ANSB060 could also relieve the alterations in hepatic morphology, improve digestive enzyme activities of hepatopancreas and intestine, as well as decrease AFB1 residues in carp's hepatopancreas and gonad. It is concluded that ANSB060 has a protective effect in carp with aflatoxicosis, with a promising potential in feed industrial applications.
外文关键词：Bacillus subtilis；Aflatoxin-detoxifying agent；Growth performance；Digestive enzymes；Residue；Yellow River carp
作者：Fan, Y；Liu, LT；Zhao, LH；Wang, XP；Wang, DC；Huang, CR；Zhang, JY；Ji, C；Ma, QG
作者单位：China Agr Univ
期刊名称：FOOD AND CHEMICAL TOXICOLOGY
期刊影响因子：3.584
出版年份：2018
出版刊次：3
点击下载：枯草芽孢杆菌ANSB060对饲喂了黄曲霉毒素B1污染饲料的黄河鲤鱼的生长、消化酶及黄曲霉毒素残留的影响