中文摘要：黄曲霉毒素是许多食品如花生、香料、大米、坚果及玉米中自然发生的次生代谢物。黄曲霉毒素是遗传毒性物质并能致癌，造成严重的不良健康影响。本研究旨在评估食用黄曲霉毒素污染的花生及花生制品的概率风险。结果表明，虽然黄曲霉毒素污染似乎在很大程度上不能解释台湾肝癌的发生，但暴露限值（MOE）计算指出，它可能引起潜在的健康问题。
外文摘要：Aflatoxins are secondary metabolites naturally occurring in many foods such as peanuts, spices, rice, tree nuts, and maize. Aflatoxins are both genotoxic and carcinogenic substances and can cause severe adverse health effects. The purpose of this study is to estimate the probabilistic risk of consuming aflatoxin-contaminated peanuts and peanut products. Concentration data (1.84 ± 4.03 ppb) were gathered from the Taiwan Food and Drug Administration (TFDA) between 2005 and 2015, along with consumption rate data (from Nutrition and Health Survey in Taiwan) for five age groups, namely 1-2 years (babies), 3-9 years (toddlers), 10-17 years (teenagers), 18-65 years (adults), and above 65 (elderly), in two sub-populations (whole group and consumer only). These data are essential material for exposure analysis. According to the benchmark dose lower confidence limit 10% (BMDL10) (170 ng/kg bw/day) suggested by the European Food Safety Authority (EFSA), the calculated margin of exposure (MOE) value cannot reach 10,000. Cancer potency data from Joint FAO/WHO Expert Committee on Food Additives (JECFA) indicates that the estimated population risk ranges from 0.0007 to 0.2713 cancers/100,000 population/year. Although aflatoxin contamination does not seem to largely account for the occurrence of liver cancer in Taiwan, MOE calculations point out that it may cause potential health concerns.
外文关键词：aflatoxin；risk assessment；Taiwan；peanut
作者：Wang, X；Lien, KW；Ling, MP
作者单位：Natl Taiwan Ocean Univ
期刊名称：FOOD CONTROL
期刊影响因子：3.388
出版年份：2018
出版刊次：9
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