中文摘要：黄曲霉毒素是一种食品污染物，普遍存在于膳食中。长期膳食黄曲霉素暴露的人群，其肝癌的发生与食品中黄曲霉毒素污染率高有关。因此，本研究旨在确定马来西亚雪兰莪州葫芦朗格区成人黄曲霉毒素暴露的生物标志物—尿黄曲霉毒素M1（AFM1）与饮食摄入的关系。卡方分析显示蛋类(X² = 4.77, p = 0.03)和乳制品(X² = 19.36, p < 0.01) 的消费与尿AFM1显著相关，但两类食品消费人群的Phi 和Cramer's V值小于0.3，表明这类食品消费人群与尿AFM1水平之间的相关性较弱。
外文摘要：Aflatoxin is a food contaminant and its exposure through the diet is frequent and ubiquitous. A long-term dietary aflatoxin exposure has been linked to the development of liver cancer in populations with high prevalence of aflatoxin contamination in foods. Therefore, this study was conducted to identify the association between urinary aflatoxin M₁ (AFM₁), a biomarker of aflatoxin exposure, with the dietary intake among adults in Hulu Langat district, Selangor, Malaysia. Certain food products have higher potential for aflatoxin contamination and these were listed in a Food Frequency Questionnaire, which was given to all study participants. This allowed us to record consumption rates for each food product listed. Concomitantly, urine samples were collected, from adults in selected areas in Hulu Langat district, for the measurement of AFM₁ levels using an ELISA kit. Of the 444 urine samples collected and tested, 199 were positive for AFM₁, with 37 of them exceeding the limit of detection (LOD) of 0.64 ng/mL. Cereal products showed the highest consumption level among all food groups, with an average intake of 512.54 g per day. Chi-square analysis showed that consumption of eggs (X² = 4.77, p = 0.03) and dairy products (X² = 19.36, p < 0.01) had significant associations with urinary AFM₁ but both food groups were having a phi and Cramer's V value that less than 0.3, which indicated that the association between these food groups' consumption and AFM₁ level in urine was weak.
外文关键词：aflatoxin；aflatoxin M-1；urinary AFM(1)；dietary intake；Hulu Langat；Malaysia
作者：Sulaiman, SH；Jamaluddin, R；Sabran, MR
作者单位：Univ Putra Malaysia
期刊名称：NUTRIENTS
期刊影响因子：3.759
出版年份：2018
出版刊次：4
点击下载：马来西亚雪兰莪葫芦朗格区成人尿液黄曲霉毒素（AFM1）与膳食摄入的关系