中文摘要：本研究分析了从我国电商网店中收集的200个谷物食品中的脱氧雪腐镰刀菌烯醇（DON），一种由各种镰刀菌产生的霉菌毒素。所分析的谷物食品中，成人与儿童慢性（长期）及急性（短期）DON暴露评估表明，面粉(多用途面粉和全麦面粉)、馒头及饼干已成为中国人饮食潜在健康危害的来源。而玉米粉及燕麦片中与DON污染有关的风险也不容忽视。
外文摘要：Deoxynivalenol (DON), a mycotoxin produced by various Fusarium species, was analyzed in 200 cereal-based food products collected from e-commerce stores in China. Optimized methods using immunoaffinity column (IAC) clean-up coupled with UV detection were applied. DON was detected in 87.5% (12.5–1920.4 μg/kg) of samples, and 10.5% of tested samples exceeded the legal limit for DON in China (1000 μg/kg). DON was found in 100% of whole wheat flour (51.6–1308.9 μg/kg), Chinese steamed bread (54.5–845.4 μg/kg), and biscuit (40.9–1920.4 μg/kg), samples, and in 85.3% of all-purpose flour (12.5–1285.4 μg/kg), 73.3% of maize flour (26.4–138.2 μg/kg), and 60.0% of oat flake samples (16.8–243.6 μg/kg), with 426.0, 293.0, 419.2, 455.7, 55.4, and 44.0 μg/kg, respectively, representing the mean levels in these products. A chronic intake assessment indicated that estimated dietary intake (EDI) of DON through the consumption of wheat flour was 1.0–3.8 and 3.1–11.3 times that of the Provisional Maximum Tolerable Daily Intake (PMTDI) of 1.0 μg/kg body weight/day for adults and children, respectively, at different levels. The EDIs of DON consumed through wheat flour-derived products (Chinese steamed bread and biscuits) for children was 1.7–12.7 times those of the PMTDI at different levels, whereas the EDIs obtained through consumption of maize flour and oat flakes were 0.2 times lower than those of the PMTDI for both adults and children. In a dietary exposure assessment, the acute hazard indexes (aHI) for adults and children were above 100% of Acute Reference Dose (ARfD) of 8.0 μg/kg body weight/day) through the consumption of wheat flour, Chinese steamed bread, and biscuits, and the aHIs were only 16.4% (31.2%) and 5.1% (8.3%) of ARfD for adults (children). Among the cereal-based food products analyzed, both chronic (long-term) and acute (short-term) dietary exposure assessments for DON consumption by adults and children indicated that wheat flour (all-purpose flour and whole wheat flour), Chinese steamed bread, and biscuits have become sources of potential health hazards in the human diet in China. The risk associated with DON contamination in maize flour and oat flakes should also not be ignored.
外文关键词：Deoxynivalenol (DON)；HPLC；Wheat；Bread；Biscuit；Dietary exposure
作者：Ji, XF；Yang, H；Wang, JM；Li, R；Zhao, HY；Xu, J；Xiao, YP；Tang, B; Qian, MR
作者单位：Zhejiang Acad Agr Sci
期刊名称：FOOD CONTROL
期刊影响因子：3.388
出版年份：2018
出版刊次：10
点击下载：电商销售的谷物食品中脱氧雪腐镰刀菌烯醇(DON)的发生及我国消费者膳食DON暴露评估