中文摘要：脱氧雪腐镰刀菌烯醇（DON）是一种臭名昭著的霉菌毒素，主要出现在受镰刀菌污染的农作物中，给畜牧业带来巨大损失，引起严重的人体健康安全风险。本文报道了一株革兰氏阴性菌（Devosia insulae A16），能有效地生物降解DON及其衍生物，包括3-乙酰DON及15-乙酰DON。研究结果证实，该菌株可用作生物降解剂，防治粮食DON污染。
外文摘要：Deoxynivalenol (DON), a notorious mycotoxin mainly found in Fusarium-contaminated crops, causes great loss in livestock farming and severe safety risks to human health. Here we report the isolation of a Gram-negative bacterial strain with effective biodegrading abilities on DON and its derivatives including 3-acetyl-DON and 15-acetyl-DON. The strain was identified as Devosia insulae A16 on the basis of morphological and physiological characteristics and 16S rRNA-based phylogenetic analysis. D. insulae A16 was able to degrade 88% of 20 mg/l DON within 48 h under aerobic conditions at 35 °C and neutral pH. The major degradation product of DON and its derivatives was 3-keto-DON by the oxidation of the hydroxyl group at C-3. Both 3-acetyl-DON and 15-acetyl-DON underwent a deacetylation reaction to generate DON prior to the degradation to 3-keto-DON. The results provide the potential use of D. insulae A16 as a biodegradation agent to control DON contamination in cereals.
外文关键词：Deoxynivalenol；DON derivatives；Biodegradation；3-keto-DON；Devosia insulae
作者：Wang, G；Wang, YX；Ji, F；Xu, LM；Yu, MZ；Shi, JR；Xu, JH
作者单位：Jiangsu Acad Agr Sci
期刊名称：FOOD CHEMISTRY
期刊影响因子：4.052
出版年份：2019
出版刊次：3
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