中文摘要：本研究旨在弄清黄曲霉毒素B1对尼里-拉菲水牛的采食量、血液血清生化指标的影响，并比较了3种不同的AFB1吸附剂的效果。结果显示与对照相比，经AFB1处理的水牛其平均日采食量显著下降(P < 0.05)；总胆红素、碱性磷酸酶(ALP)、丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)和肌酐的血清水平显著增加(P < 0.05)，但血尿素氮(BUN)水平变化不显著(P > 0.05)；处理14、21天时，血液中的总红细胞计数(TEC)、总白细胞计数(TLC)、血红蛋白浓度(HGB)、红细胞压积水平(HCT)、红细胞平均血红蛋白（MCH）及平均红细胞血红蛋白浓度（MCHC）显著减少(P < 0.05)。从三种毒素吸附剂来看，0.2%的葡甘聚糖效果最好，对增加牛的采食量和减少牛血液血清生化指标的副作用效果显著(P < 0.05)，但不能完全抵销；水合硅铝酸钙钠（HSCAS）的效果次之，活性炭最差。
外文摘要： The objective of the study was to determine the responses of Nili-Ravi buffalo to aflatoxin B1 (AFB1) in terms of feed intake, haematological and serum biochemical parameters and to compare the efficacy of three different toxin adsorbents against AFB1. Twenty-five Nili-Ravi buffaloes were selected from a herd and were divided into five groups for a period of 21 days to receive: no aflatoxin B1 (AFB1) in the diet, a diet contaminated with AFB1, a diet contaminated with AFB1 with the addition of one of three different toxin adsorbents: glucomannan, hydrated sodium calcium aluminosilicate (HSCAS), or activated charcoal at an inclusion level of 0.2% of feed. AFB1 was incorporated into feed at an inclusion level of 500 μg · kg-1 per animal per day. The results indicate that the average daily feed intake of AFB1-treated buffaloes significantly declined (P < 0.05) compared with the control. Serum levels of total bilirubin, alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST) and creatinine were significantly increased (P < 0.05) in response to AFB1, but the change in blood urea nitrogen (BUN) levels was nonsignificant (P > 0.05). In haematology, the total erythrocyte count (TEC), total leukocyte count (TLC), haemoglobin concentration (HGB), haematocrit levels (HCT), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC) decreased significantly (P < 0.05) in the AFB1 group on days 14 and 21 of the experiment. From among the three toxin adsorbents, 0.2% glucomannan significantly (P < 0.05) improved the feed intake levels of buffaloes and also significantly (P < 0.05) minimized the AFB1-induced adverse effects on haematology and serum biochemistry, but was unable to totally ameliorate its effect, while HSCAS was less effective, and activated charcoal, the least.
外文关键词：activated charcoal；aflatoxin B1；buffalo；glucomannan；HSCAS
作者：Akhtar, R；Sardar, M；Saima；Yaqub, T
作者单位：Univ Vet & Anim Sci
期刊名称：BUFFALO BULLETIN
期刊影响因子：0.067
出版年份：2016
出版刊次：4
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