中文摘要：FoodChain-Lab是一种开源软件，该软件可用于分析食源性疾病流行事件的追踪调查与反馈分析。2011年以来，德国发生的一系列食源性疾病流行事件，事件的调查急需一款合适的软件支撑，FoodChain-Lab应运而生。该软件可以实现数据管理、数据链接、可视化展示。通过对参与调查的食品生产企业、食品零售站（公司或个人）追踪数据的计算可以鉴别出可能的致病源；同时，软件还可以支持特定食品零售站的交叉感染分析、地理分布关联分析及追踪网络结构的拓扑聚类。FoodChain-Lab已成功应用于许多食源性疾病流行事件的调查，如2011年肠出血性大肠杆菌病流行事件、2013年-2014年欧洲甲型肝炎流行事件。
外文摘要：FoodChain-Lab is modular open-source software for trace-back and trace-forward analysis in food-borne disease outbreak investigations. Development of FoodChain-Lab has been driven by a need for appropriate software in several food-related outbreaks in Germany since 2011. The software allows integrated data management, data linkage, enrichment and visualization as well as interactive supply chain analyses. Identification of possible outbreak sources or vehicles is facilitated by calculation of tracing scores for food-handling stations (companies or persons) and food products under investigation. The software also supports consideration of station-specific cross-contamination, analysis of geographical relationships, and topological clustering of the tracing network structure. FoodChain-Lab has been applied successfully in previous outbreak investigations, for example during the 2011 EHEC outbreak and the 2013/14 European hepatitis A outbreak. The software is most useful in complex, multi-area outbreak investigations where epidemiological evidence may be insufficient to discriminate between multiple implicated food products. The automated analysis and visualization components would be of greater value if trading information on food ingredients and compound products was more easily available.
外文关键词：Bacterial diseases；Biology and life sciences；Computer and information sciences；Data management；Data visualization；Ecology；Ecology and environmental sciences；Engineering and technology；Enterohaemorrhagic Escherichia coli；Escherichia coli infections；Food chains；Food consumption；Foodborne organisms；Graphs；Infectious diseases；Infographics；Medicine and health sciences；Pathogens；Pathology and laboratory medicine；Physiological processes；Physiology；Research Article；Software engineering；Software tools
作者：Armin A. Weiser；Christian Thöns；Matthias Filter等
作者单位：德国联邦风险评估研究所
期刊名称：PLoS One
期刊影响因子：3.057
出版年份：2016
出版刊次：3
点击下载：FoodChain-Lab：一种追溯反馈工具的开发及其在德国食源性疾病暴发事件中的应用