中文摘要：伏马菌素是由镰刀菌产生的霉菌毒素，能感染玉米作物。一些伏马菌素类似物因其毒性及人畜致癌力而广为人知，它们存在于玉米类食品中，因此膳食就成为这些毒素的主要暴露源，特别是对乳糜泻患者。本文的宗旨是：评估玉米类膳食中伏马菌素B1、B2和B3的总量，并评价伏马菌素对乳糜泻病人的暴露情况。结果发现，虽然样品中3种毒素含量均低于欧盟委员会第1126/2007号法规的限定，但污染程度存在多样性。评估伏马菌素对不同年龄段人群的暴露，发现有些情况值得注意：毒素的总摄入量超过了欧盟食品安全局规定的临时可耐受最高摄入量达1.5倍。因此，不管是对乳糜泻患者还是非腹腔疾病人群，针对伏马菌素总膳食暴露污染的估计均显不足。
外文摘要：Fumonisins are mycotoxins produced by Fusarium species and affecting maize crops. Some analogues of fumonisins are known for their toxic and possible carcinogenic effects on humans and animals. Because of their occurrence in corn-based food, diet is the main source of exposure to these mycotoxins, especially among people affected by celiac disease. Hence, the purpose of this paper was to evaluate the amount of fumonisins B1, B2 and B3 in maize-based products and to assess the exposure of people affected by celiac disease to fumonisins. The sample consisted of 154 gluten-free products analyzed according to method UNI EN 14352:2005. Results showed a heterogeneous contamination by fumoninisin B1, B2 and B3, although below limits of Commission Regulation No 1126/2007 and consistent with other European literature data. Exposure to fumonisins was evaluated for different age groups. In some cases exposure to fumonisins could not be ignored since the total intake could exceed EFSA Provisional Maximum Tolerable Intake up to 150%. Therefore, in the light of an overall contamination by fumonisins the total dietary exposure could be underrated not only in people affected by celiac disease, but also in non-celiac population.
外文关键词：Fumonisins；Celiac disease；Maize；Exposure assessment
作者：Esposito, F；Fasano, E；Scognamiglio, G；Nardone, A；Triassi, M；Cirillo, T
作者单位：Univ Naples Federico II
期刊名称：FOOD AND CHEMICAL TOXICOLOGY
期刊影响因子：3.584
出版年份：2016
出版刊次：11
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