中文摘要：赭曲霉毒素A（OTA）是一种给家禽、动物和人类生活带来巨大威胁的强效致癌物质。它会引发鸟类的肾毒性、免疫抑制、致突变性和致畸性。膨润土属于铝硅酸盐类，具有吸附不同分子的能力，能够有效吸附数种真菌毒素。本研究旨在评估当地的膨润土对OTA诱导的肉鸡毒理和血清生化改变的改善作用。研究结果表明，单独饲喂OTA导致体重增加减少，FCR差，总病变增加、器官相对重量和血清生化值改变，而且所有的这些变化都具有剂量依赖性。而将膨润土与OTA同时饲喂，并未改善OTA造成的各种影响。
外文摘要：Ochratoxin A (OTA), a potent carcinogen, poses a great threat to the lives of poultry, animals and humans. It causes nephrotoxicity, immunosuppression, mutagenicity and teratogenicity in birds. Bentonite clay, belonging to the subclass of aluminosilicates, has the ability to adsorb different molecules and can efficiently adsorb several mycotoxins too. The present study was designed to evaluate the ameliorative effects of locally available bentonite clay against OTA induced toxicopathological and serum biochemical alterations in broilers. For this, day old broilers were divided into 16 equal groups and were given different combinations of OTA (0.15, 0.3 and 1.0 mg/kg feed) and bentonite clay (5, 10 and 20 g/kg feed). Results indicated that feeding OTA alone caused a reduction in body weight gain, poor FCR, increased gross lesions, altered relative organ weights and serum biochemical values and all these changes occurred in a dose dependent manner. Feeding bentonite clay along with OTA did not ameliorate the OTA induced alterations in body weight, FCR, gross lesions, relative organ weights and serum biochemical parameters.
外文关键词：Broilers chicks;Ochratoxin A;bentonite clay;toxicopathology;serum biochemical parameters;body weight;FCR;organ weights
作者：Khatoon, Aisha; Khan, Muhammad Zargham; Khan, Ahrar; Javed, Ijaz
作者单位：Univ Agr Faisalabad,Pakistan.
期刊名称：PAKISTAN JOURNAL OF AGRICULTURAL SCIENCES
期刊影响因子：0.597
出版年份：2016
出版刊次：11
点击下载：由赭曲霉毒素A诱导的肉鸡毒理和血清生化改变以及当地的膨润土对这些改变的作用