中文摘要：本研究通过两个试验描述了脱氧雪腐镰刀菌烯醇(DON)引发的保育猪生长抑制的过程，并探究了海藻改性蒙脱土(AMMC) 对减轻DON影响的作用。结果表明增高AMMC水平不影响保育猪的平均日增重、平均日采食量、增重饲料比及最终体重。总的来看，试验强化了DON对猪采食量的影响，同时揭示了DON对增重饲料比的影响可能比预想的更严重。此外，部分猪表现出对DON的适应性，因为DON对平均日采食量和增重饲料比的影响随时间的延长而减弱，而添加AMMC不能抵消DON的有害影响。
外文摘要：Two experiments were conducted to characterize the progression of deoxynivalenol (DON)-induced growth suppression and to investigate algae-modified montmorillonite clay (AMMC) as a means to alleviate the effects of DON in nursery pigs. In both experiments, naturally DON-contaminated wheat was used to produce diets with desired DON levels. In Exp. 1, 280 barrows and gilts (10.0 ± 0.2 kg BW) were used in a 28-d experiment arranged in a 2 × 2 + 1 factorial design with 8 replicates per treatment. The 5 treatments consisted of 2 positive control (PC) diets with DON below detection limits and with or without 0 or 0.50% AMMC and 3 negative control (NC) diets with 5 mg/kg of DON and containing 0, 0.25, or 0.50% AMMC. No DON × AMMC interactions were observed. Overall, pigs fed DON had decreased (P < 0.001) ADG and final BW regardless of AMMC addition. Feeding DON-contaminated diets elicited the most severe depression (P < 0.001) in ADFI and G:F from d 0 to 3, remaining poorer overall (P < 0.01) but lessening in severity as exposure time increased. Pigs fed DON diets had greater (P < 0.05) within pen BW variation (CV) on d 28. Although the addition of 0.50% AMMC to diets restored (P < 0.05) ADFI from d 14 to 21 to levels similar to the PC, no other differences were observed for AMMC inclusion. In Exp. 2, 360 barrows (11.4 ± 0.2 kg BW) were used in a 21-d experiment with 9 dietary treatments arranged in a 3 × 3 factorial design with DON and AMMC inclusion as main effects. There were 8 replicate pens per treatment. Treatments consisted of 3 PC diets without DON, 3 low-DON (1.5 mg/kg DON) NC diets, and 3 high-DON (3 mg/kg DON) NC diets with 0, 0.17, or 0.50% AMMC incorporated at each DON level. No DON × AMMC interactions were observed. As DON level increased, ADG and final BW decreased (quadratic, P < 0.05), driven by decreased (quadratic, P < 0.01) ADFI and poorer (quadratic; P < 0.05) G:F. At both 1.5 and 3 mg/kg DON, reductions in ADG were most marked from d 0 to 7 (15 to 22% lower) and were least distinct from d 14 to 21 (5 to 6% lower). Incorporating AMMC at increasing levels had no effect on ADG, ADFI, G:F, or final BW. Overall, these experiments reinforce DON effects on feed intake but also indicate that the effects of DON on G:F may be more severe than previously thought. Furthermore, some pigs appear to develop tolerance to DON, as effects on ADFI and G:F lessen over time. However, the addition of AMMC did not offset the deleterious effects of DON.
外文关键词：deoxynivalenol；detoxifying agents；montmorillonite clay；nursery pig；swine；vomitoxin
作者：Frobose, HL；Erceg, JA；Fowler, SQ；Tokach, MD；DeRouchey, JM；Woodworth, JC；Dritz, SS；Goodband, RD
作者单位：Kansas State Univ
期刊名称：JOURNAL OF ANIMAL SCIENCE
期刊影响因子：2.014
出版年份：2016
出版刊次：9
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