中文摘要：本研究报道了用预警抽样计划检测黄曲霉毒素AFM1高污染的牛奶批次的灵敏度的测试结果。通过9017个从意大利执行各种处置限度(AL)控制计划的牛奶加工厂采集的样品，研究了该方法的效果。执行30ng/kg AL的牛奶加工厂， 其奶样中AFM1的污染率显著低于执行40 ng/kg AL的工厂中大于等于95%的情况。表明了控制计划能有效预警牛奶AFM1高污染的发生并采取积极措施限制污染水平。膳食暴露水平评估基于奶样中AFM1含量及意大利食品消费数据展开，评估了不同年龄段人群的每日摄入量(EDI)和危险指数(HI)。HIs显示成年人群中没有出现预期的副作用，但在3岁以下的儿童中，近似的HI值非常高。本研究强调了仔细监控牛奶和乳制品中的黄曲霉毒素M1的重要性。
外文摘要：The study reports the results of testing the sensitivity of an early warning sampling plan for detecting milk batches with high aflatoxin AFM1 concentration. The effectiveness of the method was investigated by the analysis of 9017 milk samples collected in Italian milk processing plants that applied control plans with different action limits (AL). For those milk processing plants where 30 ng kg-1 AL has been applied, the AFM1 contamination was significantly lower at or above the 95th percentile of the milk samples when compared to plants that used 40 ng kg-1 AL. The results show that the control plan can be used effectively for early warning of occurrence of high AFM1 contamination of milk and to carry out pro-active measures to limit the level of contamination. Estimation of dietary exposure was also carried out, based on the aflatoxin M1 content of the milk samples and on Italian food consumption data. Estimated Daily Intakes (EDI) and Hazard Indices (HI) were calculated for different age groups of the population. HIs show that no adverse effects are expected for the adult population, but in the case of children under age three, the approximate HI values were considerably higher. This underlines the importance of the careful monitoring and control of aflatoxin M1 in milk and dairy products.
外文关键词：Aflatoxin M-1；milk；statistical analysis；exposure assessment
作者：Kerekes, K；Bonilauri, P；Serraino, A；Giacometti, F；Piva, S；Zambrini, V；Canever, A；Farkas, Z；Ambrus, A
作者单位：Natl Food Chain Safety Off
期刊名称：Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment
期刊影响因子：1.878
出版年份：2016
出版刊次：12
点击下载：通过减少牛奶中黄曲霉毒素M1含量来减轻消费者暴露的有效自主控制策略