外文摘要：NOVELTY - The assay has a test strip comprising a single control zone (5) having a beta-lactam control zone capture agent and a mycotoxin control zone capture agent. The control zone capture agents include different affinity to the binder and capture the binder whether or not the binder forms a binder-analyte complex, where capture of the binder at test zones (4) or control zone results in a detectable signal, and greater signal in the control zone as compared to signal in one of the test zones indicates a positive result.
USE - Lateral flow assay for detecting beta-lactam analytes and mycotoxin analytes e.g. aflatoxin, vomitoxin and aflatoxin metabolites (all claimed) in a test solution to detect antibiotic residues in foods in a food products industry.
ADVANTAGE - The control zone compares to more than one test zone, thus simplifying test result interpretation. The control zone captures bound and unbound cloxacillin binder that flow past the test zone without being captured.
DETAILED DESCRIPTION - The control zone capture agents comprise an antibody or antibody binding protein such as protein A. An INDEPENDENT CLAIM is also included for a method for detecting beta-lactam analytes and mycotoxin analytes in a test solution.
DESCRIPTION OF DRAWING(S) - The drawing shows a side view of a Lateral flow assay including two test zones and a control zone.
Sample pad (1)
Solid support (2)
Nitrocellulose membrane (3)
Binder at test zones (4)
Single control zone (5)
Binder application area (7)
申请号：US9562898-B1
专利号：US9562898-B1
公开/公告号：US878178P；US461742
申请/专利权人：CHARM SCI INC (CHAR-N)
发明/设计人：SAUL, S J；MARKOVSKY, R J；DOUGLAS, D W
主分类号：G01N-033/544；G01N-033/558
点击下载：侧向横流法用于检测食品业加工的食品中抗生素残留测试液中的黄曲霉毒素，具有控制区捕获剂，捕获形成/没形成粘合剂-分析物复合物的粘合剂