中文摘要：研究开发了一种基于右旋四肽超分子水凝胶的新型疫苗。注射前，通过涡旋或温和摇动抗原就可以附着到水凝胶中。这种疫苗能够刺激CD8+T细胞反应，从而显著抑制肿瘤生长。该疫苗能够产生更多的亚单位疫苗，从而有助于产生更多的抗体。
外文摘要：A novel vaccine adjuvant based on a supra-molecular hydrogel of a D-tetrapeptide is reported. Antigens can be easily incorporated into the hydrogel by a vortex or by gently shaking before injection. The vaccines can stimulate strong CD8+ T-cell responses, which significantly inhibits tumor growth. This novel adjuvant is expected to enable a wide range of sub-unit vaccines and help the production of antibodies.
外文关键词：IN-VIVO; IMMUNE-RESPONSES; NANOPARTICLES; EFFICACY; PROMOTE; FUTURE; HIV
作者：Luo, ZC; Wu, QJ; Yang, CB; Wang, HM; He, T; Wang, YZ; Wang, ZY; Chen, H; Li, XY; Gong, CY; Yang, ZM
作者单位：四川大学
期刊名称：ADVANCED MATERIALS
期刊影响因子：18.96
出版年份：2017
出版刊次：2
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