中文摘要：研究分析了兰德瑞斯品系（La）进行猪肺炎支原体肺部病变性状选育对三元杂交商品猪（LaWaDa）肺炎支原体抗性和免疫能力的影响。结果表明：LaWaDa的肺部病变情况高于选育的亲本La，但显著低于未经选育的杂交系LbWbDb；LaWaDa骨髓细胞水平低于La和LbWbDb，T细胞水平高于这两个群体；免疫后，LaWaDa 外周血中IL-6、IL-10、转化生长因子β和IFN-γ的m RNA水平显著高于La和LbWbDb；这些结果表明，选育后La系对肺炎支原体的抗性和一些优良的免疫性状能够通过三元杂交传递到后代群体。
 
外文摘要：To clarify the genetic influence of mycoplasmal pneumonia of swine (MPS) lesion-selected Landrace (La) on MPS resistance and immune characteristics in three-way crossbred pigs (LaWaDa), the LaWaDa pigs were compared with the non-selected crossbred (LbWbDb) and purebred (La) pigs. The MPS lesion score in the three lines was as follows: La line < LaWaDa line < LbWbDb line, with significant differences among the lines. The proportions of myeloid cells and T cells were lower and higher, respectively, in the LaWaDa pigs compared with those in the other two lines. Messenger RNA (mRNA) expression of interleukin (IL)-6, IL-10, transforming growth factor-beta, and interferon-gamma in peripheral blood was significantly increased after vaccination in the La and LaWaDa lines. IL-4 mRNA expression in the LaWaDa line was intermediate to the La and LbWbDb lines. Furthermore, principal component analysis for immune traits and MPS lesions was executed to clarify the characteristics of each pig line. These findings suggest that the immune responses in the three pig lines are genetically distinct and that MPS resistance and some immunity characteristics from the La line were transmitted to the three-way crossbred pigs.
外文关键词： disease resistance; immunogenic property; mycoplasma pneumonia lesion; three-way crossbred pig
作者：Borjigin, L; Shimazu, T; Katayama, Y; Watanabe, K; Kitazawa, H; Roh, S; Aso, H; Katoh, K; Satoh, M; Suda, Y; Sakuma, A; Nakajo, M; Suzuki, K
作者单位：日本东北大学
期刊名称：ANIMAL SCIENCE JOURNAL
期刊影响因子：1.045
出版年份：2017
出版刊次：4
点击下载：兰德瑞斯品系猪肺炎支原体肺部病变性状选育对提高三元杂交商品猪肺炎支原体抗性和免疫能力的效果分析