中文摘要:本发明公开了一种佐剂及其组成;该佐剂由皂苷、固醇、季胺、二乙基氨基乙基(DEAE)葡聚糖或油类。该佐剂可以增强对抗原的免疫反应,而不会对机体产生毒性或副作用。
外文摘要:NOVELTY - Adjuvant formulation comprises saponin, a sterol, a quaternary amine and diethylaminoethyl (DEAE) dextran or oil.
USE - Adjuvant formulation used in vaccine for preparing medicament for treating or preventing infectious disease, preferably mastitis (all claimed).
ADVANTAGE - Adjuvant formulation enhances the immune response to antigens, without producing toxic or undesirable side effects in the subject.
主权项:DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for:(1) a vaccine, which comprises antigen component and the adjuvant formulation; and (2) a method for treating or preventing an infectious disease, which involves administering to a subject the vaccine.
公开/公告号:AU2017201506A1
公开/公告日:2017-03-06
申请/专利权人:ZOETIS SERVICES LLC (PFIZ-C)
发明/设计人:BAGI, C M;CHILDERS, T A;DOMINOWSKI, P J;KREBS, R L;MANNAN, R M;OLSEN, M K;THOMPSON, J R;WEERATNA, R D;YANCEY, R J;ZHANG, S
主分类号:A61K39/00; A61K39/012; A61K39/02; A61K39/39
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