中文摘要:本发明公开了一种佐剂及其构成,该佐剂由一种亲油层、丙烯酸或甲基丙烯酸聚合物、生理盐水、胆固醇、皂苷和氢氧化钠组成。
外文摘要:The present disclosure provides for an adjuvant composition that is suited for injectable as well as transdermal administration. The adjuvant composition generally comprises a lipophile, a polymer of acrylic or methacrylic acid, saline, cholesterol, a saponin, and sodium hydroxide. A vaccine composition is also provided for that generally includes the vaccine composition of the present disclosure and a DNA component. A method for vaccinating animals and humans utilizing the adjuvant composition of the present disclosure is also provided.
主权项:(1) a vaccine composition comprising an adjuvant composition defined above and an antigen; and
(2) a method of eliciting an immune response by administering a single dose of the adjuvant or vaccine composition defined above to an animal or an animal.
公开/公告号:WO2016154432A1
公开/公告日:2016-09-29
申请/专利权人:VAXLIANT LLC (VAXL-N)
发明/设计人:MILLER, T J;PFANNENSTIEL, M A
分类号:A61K39/0258; A61K39/145; A61K39/39; A61K2039/521; A61K2039/53; A61K2039/55511; A61K2039/55577; C12N2760/16134
主分类号:A61K31/00; A61K39/00; A61K39/39
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