软腐果胶杆菌的尾部裂解噬菌体

Tailed Lytic Bacteriophages of Soft Rot Pectobacteriaceae

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中文摘要:软腐果胶杆菌科(SRP)包括果胶杆菌属和Dickeya属,其生态和进化特性的研究涉及细菌病毒(噬菌体)。通常认为噬菌体是生态安全和高度特异性保护植物和作物免受细菌性疾病侵害的一种有前景的工具。近年来,有关噬菌体的信息增长迅速,其中包括新的基于基因组学的分类分布原则。本综述总结了出版物和基因组数据库中有关感染果胶杆菌和Dickeya的噬菌体的数据。该分析不仅强调了噬菌体的主要基因组特性,并据此将它们分类到科和属,还强调了它们可能适用于噬菌体控制应用的特征。具体讨论了噬菌体识别受体的分子机制以及与噬菌体抗性突变体进化有关的问题。
外文摘要:The study of the ecological and evolutionary traits of Soft Rot Pectobacteriaceae (SRP) comprising genera Pectobacterium and Dickeya often involves bacterial viruses (bacteriophages). Bacteriophages are considered to be a prospective tool for the ecologically safe and highly specific protection of plants and harvests from bacterial diseases. Information concerning bacteriophages has been growing rapidly in recent years, and this has included new genomics-based principles of taxonomic distribution. In this review, we summarise the data on phages infecting Pectobacterium and Dickeya that are available in publications and genomic databases. The analysis highlights not only major genomic properties that assign phages to taxonomic families and genera, but also the features that make them potentially suitable for phage control applications. Specifically, there is a discussion of the molecular mechanisms of receptor recognition by the phages and problems concerning the evolution of phage-resistant mutants.
外文关键词:bacteriophage;Pectobacterium;Dickeya;taxonomy;morphology;genomics;phage control;adsorption;tail spike protein
作者:Miroshnikov, KA;Evseev, PV;Lukianova, AA;Ignatov, AN
作者单位:Russian Acad Sci;Russian State Agr Univ;Lomonosov Moscow State Univ;RUDN Univ
期刊名称:MICROORGANISMS
期刊影响因子:4.152
出版年份:2021
出版刊次:9
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  1. 编译服务:噬菌体
  2. 编译者:虞德容
  3. 编译时间:2021-10-14